#!/usr/bin/env python import PySimpleGUI as sg # Example .disappear() .reappear() methods in window layout = [[ sg.Text('My Window') ], [ sg.Button('Disappear')]] window = sg.Window('My window', layout) while True: event, values = window.read() if event == sg.WIN_CLOSED: break if event == 'Disappear': window.disappear() sg.popup('Click OK to make window reappear') window.reappear() window.close()